Symptoms in Mice Lacking a Single Receptor Type Mimic the Development of Schizophrenia

Deleting one type of neurotransmitter receptor in a specific population of brain cells can induce schizophrenia-like behavior in mice, but only when the receptor is deleted early in development, according to a study by NIMH intramural scientists. The work provides strong support for previous observations implicating these receptors in psychosis; further, the mice provide a model of how psychotic symptoms can arise from a disruption in neuronal development, consistent with observations of how schizophrenia emerges in humans.

Submitted by Anna

Welcome to The SARDAA Blog

MPj03864970000[1]Welcome to the SARDAA Blog. We plan to provide regular updates regarding, among other things, NIMH and research updates, SARDAA developments, new partnerships, and mental health related legislative updates. 

We want this Blog to be interactive, allowing for suggestions, comments and helpful offerings.  SARDAA is a grassroots not-for-profit organization offering hope, dignity and a voice for people impacted by schizophrenia and related disorders.